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  OsSatura

Comprised of 20% beta-TCP (ß-TCP) and 80% HA, OsSatura BCP™ mimics the structure of natural cancellous bone and degrades in stages that balance the need for rapid bone in growth and long-term support.1 Its consistent, interconnected macropores promote vascular infiltration, nutritional transport and cell colonization, while a 3-dimensional, microporous architecture creates a favorable environment for BMPs and osteogenic precursor cells with an average porosity of 50%.
The slower degrading, porous HA component provides long-term support and recruits endogenous BMPs that convert stem cells into bone-forming cells as the faster degrading ß-TCP undergoes dissolution and reprecipitation.2

1. Vacarro AR. The role of the osteoconductive scaffold in synthetic bone graft. Orthopedics 2002;25(5)s571-8.
2. El-Ghannam A, Ducheyne P, Shapiro IM, et al. Effect of serum proteins on osteoblast adhesion to surface-modified bioactive glass and hydroxyapatite. J Orthop Res 1999 (30):340-5.