The Allograft with Optimal Handling and Potential Osteoinductive Properties Accell Connexus outpaces other allograft products in three key ways: • Superior processing • Validated in vitro assay to confirm the osteoinductivity of each DBM lot • Sterile - product is e-beam sterilized The RPM Carrier Accell Connexus contains a reverse-phase medium that offers exceptional handling. The result is a graft that is contained and resistant to irrigation. Accell Connexus is moldable without becoming hard, packable into virtually any size or shape defect, and easy to combine with other graft materials. An independent study of the comparative efficacy of two different bone matrix allografts, in which the RPM product had a higher success rate than the product without RPM.1. RPM is inert, biocompatible, and safe. The majority of the RPM IsoTis uses is metabolized by the kidneys within the first day, presenting a safe means of excretion.2 Osteoinductivity Assay Each lot of DBM used to create Accell technology passes a validated in vitro assay to ensure osteoinductivity and maximum bone formation potential.3 E-beam Sterilized Accell Connexus is irradiated with a low-dose electron beam, a process that has been demonstrated to preserve the osteoinductivity.4,5 |